GREEN TEA SKIN
IN-VIVO ANTIOXIDANT EVALUATION

PARTICULARS
An in-vivo study evaluating the antioxidant efficacy of GreenTeaSkin’s patent-pending topical formula was conducted during February, 2006. The study was designed and conducted by the independent testing firm Clinical Research Laboratories, Inc., Piscataway, N.J.

The study objective was to determine the formula’s ability to quench (eliminate) skin-damaging free radicals from UV radiation on the skin of human test subjects.

STUDY RATIONALE
Free radicals (unstable, toxic molecules) are detrimental to skin cell integrity. They are acknowledged to contribute to the development of skin cell oxidation, collagen and elastin breakdown, cross-linking, pre-cancers, hyperpigmentation, and cellular inflammation.

Antioxidants (beneficial synthetic or natural micro-substances) are acknowledged to help eliminate skin-damaging free radicals.

The phyto-constituent EGCG (Green Tea’s active antioxidant) is acknowledged to be especially effective for skin cell protection and repair from free radicals.

A clinical test was employed to determine the ability of GreenTeaSkin (containing standardized EGCG) to eliminate free radicals on the surface of subjects’ skin.

Although many topical antioxidant formulas claim the inclusion of antioxidants, the antioxidant activity of these formulas is not borne out when applied to skin.

Reasons for this include that these formulas 1) do not incorporate antioxidants in sufficient amounts; 2) the antioxidants themselves are not of sufficient potency or level of standardization; 3) the antioxidants are not targeted for skin benefit; 4) fragile antioxidants degrade in-formula over time; and/or 5) because the packaging system does not prevent oxidation from light or air.

METHODS
The tested subject panel consisted of 11 (eleven) healthy Caucasian adult men and women representing Fitzpatrick Skin Types 1, 2, and 3.

GreenTeaSkin was applied to areas of the forearms of test subjects. Beta-carotene solution (as the base/control, whose measured antioxidant activity in this test application is known) was applied to other, distinctly separated areas of forearms of test subjects.

Test subjects’ skin was then irradiated by UVA/B generators to produce, over time, free radical assault and degradation of the test protective antioxidants.

An analysis was then conducted measuring GreenTeaSkin and the base/control antioxidant to determine comparative effectiveness in quenching free radicals on skin.

CONCLUSIONS
GreenTeaSkin eliminates free radicals on contact (and with sustained action) on the skin of human subjects.

GreenTeaSkin’s ability to eliminate free radicals on skin consistently outperformed the base/control antioxidant in all subjects at all points of evaluation.

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